Synthesis and in Vitro Anticancer Activity of New Thiadiazolines and Thiazolinones Containing a Chromenyl Scaffold

نویسندگان

  • I. IONUŢ
  • C. NASTASĂ
  • J. T. NDONGO
  • C. BRUYÈRE
  • H. LECLERCQZ
  • B. TIPERCIUC
  • F. LEFRANC
  • A. PÎRNĂU
  • R. KISS
  • O. ONIGA
چکیده

I. IONUŢ, C. NASTASĂ, J. T. NDONGO, C. BRUYÈRE, H. LECLERCQZ, B. TIPERCIUC, F. LEFRANC, A. PÎRNĂU, R. KISS, O. ONIGA Iuliu Haţieganu University of Medicine and Pharmacy, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, 41 Victor Babeş Street, RO400010 Cluj-Napoca, România Département de Chimie, Ecole Normale Supérieure de Yaoundé, B.P. 47, Université de Yaoundé I, Cameroun Laboratoire de Toxicologie, Faculté de Pharmacie, Université Libre de Bruxelles (ULB), Campus de la Plaine, Boulevard du Triomphe, 1050 Bruxelles, Belgique Service de Neurochirurgie, Hôpital Erasme, ULB, Bruxelles, Belgique National Institute for Research and Development of Isotopic and Molecular Technologies, RO-400293 Cluj-Napoca, Romania

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Design and Synthesis of Novel Triazole-based Peptide Analogues as Anticancer Agents

Cancer disease is a great concern in the worldwide public health and current treatments do not give satisfactory results, so, developing novel therapeutic agents to combat cancer is highly demanded. Nowadays, anticancer peptides (ACPs) are becoming promising anticancer drug candidates. This is due to several advantages inherited in peptide molecules, such as being usually with small size, high ...

متن کامل

Design and Synthesis of Novel Triazole-based Peptide Analogues as Anticancer Agents

Cancer disease is a great concern in the worldwide public health and current treatments do not give satisfactory results, so, developing novel therapeutic agents to combat cancer is highly demanded. Nowadays, anticancer peptides (ACPs) are becoming promising anticancer drug candidates. This is due to several advantages inherited in peptide molecules, such as being usually with small size, high ...

متن کامل

Synthesis and anticancer activity assay of novel chalcone sulfonamide derivatives

Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...

متن کامل

Synthesis and anticancer activity assay of novel chalcone sulfonamide derivatives

Chalcones, or 1,3–diaryl–2–propen–1–ones, one of the major classes of natural products and posses many useful properties like anticancer, antibacterial, antifungal, anti–inflammatory, antimalarial and anti–diabetic activity. We report in this communication the synthesis and anticancer study of a number of novel chalcone sulfonamides. Our results indicate that the synthesis of chalcone sulfonami...

متن کامل

Synthesis, Characterization and In-vitro Evaluation of Novel Naphthoquinone Derivatives and Related Imines: Identification of New Anticancer Leads

Quinones such as 1,4-naphthoquinones are abundant in nature and naphthoquinone based natural products are known to possess anticancer activity. This pharmacophore is known to convey anticancer activity to some drugs such as streptonigrin, mitomycin A, etc. We synthesized and characterized different classes of naphthoquinone derivatives including bis naphthoquinone, 2-arylaminonaphthoquinone, be...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013